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HO-Ser/Thr GalNAc(alpha1-O)-Ser/Thr
This enzyme catalyzes the GalNAc-transfer from UDP-GalNAc to Ser or Thr residue in the protein. The product is GalNAc-alpha-O-Ser/Thr structure, so-called Tn-antigen, which is the base structure of mucin type O-glycan. The acceptor substrate (protein) is typically Mucin. GALNT15 is the 15th member of this enzyme family. This isozyme exhibits unique catalytic activity producing multiple-GalNAc peptides.

O-glycan Tn-antigen mucin tumor marker

UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase

GGDB SymbolGALNT15
Alias GALNT16, GALNT20, GALNTL3, DKFZp434I2216, DKFZp761D2324, PIH5, GALNT7, GALNT13, GALNTL2    details
DesignationUDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase T15
OrganismHomo sapiens
GeneID 117248
HGNC 21531
mRNA AB078149       (CDS)
Protein BAD29961       (CDS)
map3p25.1
EC# 2.4.1.41   
CAZy GT27   
OMIM 615131   
This page does not indicate all of the enzymatic reaction, and expression of "GALNT15".