HS6ST3 encodes heparan sulfate-glucosamine 6-sulfotransferase 3. Heparan sulfate is composed from disaccharide units of HexA and GlcNAc/GlcNSO3 with sulfation. HS6ST catalyzes the sulfation of N-sulfated GlcNAc at C6 position. HS6ST has three types of isoenzymes in humans, and their expression tissues and substrate specificities are different.
Keyword:
heparan sulfate
, heparin
, proteoglycan
, sulfotransferase
Sulfotransferases
| HS6ST3 Alias | |
| Designation | heparan sulfate 6-O-sulfotransferase 3 |
| Organism | Homo sapiens |
| GeneID | 266722 |
| HGNC | HS6ST3 (19134) |
| mRNA | NM_153456 |
| map | 13q32. |
| Protein | NP_703157 |
| EC# | |
| CAZy | |
| GlyCosmos Glycogenes | HS6ST3 |
| OMIM | 609401 |
| GDGDB | |
| Human Protein Atlas | ENSG00000185352 |
Mus musculus
Rattus norvegicus