GAL3ST1

Last Update:2016-01-29

Galactose-3-O-sulfotranasferases 1 (GAL3ST1), also called as GalCer sulfotransferase or cerebroside sulfotransferase (CST) transfers a sulfate group from the donor substrate (PAPS), to the C3 position of the nonreducing terminal b-Gal residue of acceptor glycolipids. GAL3ST1-deficient mice demonstrated that sulfoglycolipids play important roles in myelin function and spermatogenesis.

Keyword: brain ,  galactosylceramide ,  myelin
GalCer
PAPS 		Sulfo-3GalCer
LacCer
PAPS 		Sulfo-3LacCer
GalAAG
PAPS 		Sulfo-3GalAAG

Sulfotransferases


GGDB Symbol GAL3ST1    Alias
Designationgalactosylceramide 3-O-sulfotransferase
OrganismHomo sapiens
GeneID 9514
HGNC GAL3ST1 (24240)
mRNA NM_004861
map22q12.2
Protein NP_004852
EC# 2.8.2.11   
CAZy
GlyCosmos Glycogenes GAL3ST1
OMIM 602300
Disease name
GDGDB
Human Protein Atlas ENSG00000128242
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Orthologous Gene

Acceptor Substrates (Reference)

Acceptor Substrates (KEM-C)

Expression

RNA Expression from Human Protein Atlas
This RNA expression data uses "HPA data" from the Human Protein Atlas. Tissue RNA Expression

data available from v22.proteinatlas.org

Expression (Reference)

Gene Ontology

This page does not indicate all of the enzymatic reaction, and expression of "GAL3ST1".