GGDB:

CHST15 encodes carbohydrate sulfotransferase 15. This enzyme is involved in the biosynthesis of highly sulfated chondroitin sulfate; CHST15 has C4S-6ST activity to transfer sulfate to C-6 position using sulfated GalNAc at C-4 position as an acceptor substrate to synthesize CS-E units.

Keyword: chondroitin , chondroitin sulfate , proteoglycan , sulfotransferase

Sulfotransferases

GGDB Symbol

CHST15 Alias

Designation

N-Acetylgalactosamine 4-sulfate 6-O-sulfotransferase

Organism

Homo sapiens

GeneID

51363

HGNC

CHST15 (18137)

mRNA

NM_015892

map

10q26

Protein

NP_056976

EC#

CAZy

GlyCosmos Glycogenes

CHST15

OMIM

608277

Disease name

GDGDB

Human Protein Atlas

ENSG00000182022

Mus musculus

mRNA	NM_029935
Protein	NP_084211

Rattus norvegicus

mRNA	NM_173310
Protein	NP_775432

J. Biol. Chem. 2001-11-01 ;276(47):43894-900.

Human N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase cDNA is related to human B cell recombination activating gene-associated gene.

Ohtake S. et al. PMID:11572857

J. Biol. Chem. 2003-10-01 ;278(40):38443-52.

A unique nonreducing terminal modification of chondroitin sulfate by N-acetylgalactosamine 4-sulfate 6-o-sulfotransferase.

Ohtake S. et al. PMID:12874280

RNA Expression from Human Protein Atlas

This RNA expression data uses "HPA data" from the Human Protein Atlas. Tissue RNA Expression

data available from v22.proteinatlas.org

CHST15

Sulfotransferases

Orthologous Gene

Mus musculus

Rattus norvegicus

Acceptor Substrates (Reference)

Human N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase cDNA is related to human B cell recombination activating gene-associated gene.

A unique nonreducing terminal modification of chondroitin sulfate by N-acetylgalactosamine 4-sulfate 6-o-sulfotransferase.

Acceptor Substrates (KEM-C)

Expression

Expression (Reference)

Gene Ontology