ST3GAL3, β-galactoside α-2,3-sialyltransferase 3, transfers sialic acid from CMP-sialic acid to the Galβ1→3/4GlcNAc-R. ST3GAL3 is also known as ST3N or SIAT6. ST3GAL3 is involved in synthesis of sialyl Lewis a (NeuAcα2→3Galb1→3(Fucα1→4)GlcNAc-R). Homozygous mutations found in ST3GAL3 gene are suggested to cause mental retardation.
Keyword:
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JCGG-STR002827
GlyTouCan:
G00049MO
GlyCosmos Glycans:
G00049MO
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JCGG-STR031358
GlyTouCan:
G79536OW
GlyCosmos Glycans:
G79536OW
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JCGG-STR013782
GlyTouCan:
G00055MO
GlyCosmos Glycans:
G00055MO
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JCGG-STR031527
GlyTouCan:
G00065MO
GlyCosmos Glycans:
G00065MO
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Sialyltransferase
| ST3GAL3 Alias | |
| Designation | CMP-NeuAc:Gal beta1,3(4)GlcNAc alpha 2,3-sialyltransferase |
| Organism | Homo sapiens |
| GeneID | 6487 |
| HGNC | ST3GAL3 (10866) |
| mRNA | NM_006279 |
| map | 1p34.1 |
| Protein | NP_006270 |
| EC# | 2.4.99.6 |
| CAZy | GT29 |
| GlyCosmos Glycogenes | ST3GAL3 |
| OMIM | 606494 |
| GDGDB | |
| Human Protein Atlas | ENSG00000126091 |
Mus musculus
Rattus norvegicus
