ST6GALNAC1

Last Update:2016-01-13

ST6GALNAC1, N-acetylgalactosaminide α-2,6-sialyltransferase 1, transfers sialic acid from CMP-sialic acid to the GalNAc-Ser/Thr structure on glycoproteins, such as fetuin and asialo-bovine submaxillary mucin. ST6GALNAC1 is also called as STYI or SIAT7A. ST6GALNAC1 mainly synthesize sialyl-Tn, as well as 2,6sialyl-T and disialyl-T O-glycans, which is expressed in many cancer cells.

Keyword: cancer ,  sialyl-Tn

CMP-Neu5Ac
JCGG-STR025718
GlyTouCan: G57321FI
GlyCosmos Glycans: G57321FI
JCGG-STR005242
GlyTouCan: G36123IU
GlyCosmos Glycans: G36123IU

CMP-Neu5Ac
JCGG-STR021049
GlyTouCan: G94435QH
GlyCosmos Glycans: G94435QH
JCGG-STR028041
GlyTouCan: G47180UC
GlyCosmos Glycans: G47180UC

CMP-Neu5Ac
JCGG-STR025718
GlyTouCan: G57321FI
GlyCosmos Glycans: G57321FI
JCGG-STR005242
GlyTouCan: G36123IU
GlyCosmos Glycans: G36123IU

CMP-Neu5Ac
JCGG-STR025711
GlyTouCan: G00031MO
GlyCosmos Glycans: G00031MO
JCGG-STR026818
GlyTouCan: G56682BC
GlyCosmos Glycans: G56682BC

CMP-Neu5Ac
JCGG-STR025535
GlyTouCan: G65562ZE
GlyCosmos Glycans: G65562ZE
JCGG-STR026341
GlyTouCan: G01614ZM
GlyCosmos Glycans: G01614ZM

Sialyltransferase


GGDB Symbol ST6GALNAC1    Alias
DesignationGalNAc alpha-2, 6-sialyltransferase I
OrganismHomo sapiens
GeneID 55808
HGNC ST6GALNAC1 (23614)
mRNA NM_018414
map17q25.1
Protein NP_060884
EC# 2.4.99.3   
CAZy GT29   
GlyCosmos Glycogenes ST6GALNAC1
OMIM 610138
Disease name
GDGDB
Human Protein Atlas ENSG00000070526
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Orthologous Gene

Acceptor Substrates (Reference)

Acceptor Substrates (KEM-C)

Expression

RNA Expression from Human Protein Atlas
This RNA expression data uses "HPA data" from the Human Protein Atlas. Tissue RNA Expression

data available from v22.proteinatlas.org

Expression (Reference)

Gene Ontology

This page does not indicate all of the enzymatic reaction, and expression of "ST6GALNAC1".