ST6GALNAC4

Last Update:2016-01-29

ST6GALNAC4, N-acetylgalactosaminide α-2,6-sialyltransferase 4, transfers sialic acid from CMP-sialic acid to the NeuAcα2→3Galβ1→3GalNAc-R structure on glycoproteins such as fetuin but not asialofetuin. ST6GALNAC4 is also called as SIAT7D and SIAT3C. ST6GALNAC4 is a candidate enzyme to synthesize disialy-T structures, NeuAcα2→3Galβ1→3(NeuAcα2→6)GalNAc-Ser/Thr in O-glycans.

Keyword: disialyl-T ,  sialyl-T

CMP-Neu5Ac
JCGG-STR025535
GlyTouCan: G65562ZE
GlyCosmos Glycans: G65562ZE
JCGG-STR026341
GlyTouCan: G01614ZM
GlyCosmos Glycans: G01614ZM

CMP-Neu5Ac
JCGG-STR025535
GlyTouCan: G65562ZE
GlyCosmos Glycans: G65562ZE
JCGG-STR026341
GlyTouCan: G01614ZM
GlyCosmos Glycans: G01614ZM

Sialyltransferase


GGDB Symbol ST6GALNAC4    Alias
DesignationGalNAc alpha-2, 6-sialyltransferase IV
OrganismHomo sapiens
GeneID 27090
HGNC ST6GALNAC4 (17846)
mRNA NM_014403
map9q34
Protein NP_055218
EC# 2.4.99.7   
CAZy GT29   
GlyCosmos Glycogenes ST6GALNAC4
OMIM 606378
Disease name
GDGDB
Human Protein Atlas ENSG00000136840
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Orthologous Gene

Acceptor Substrates (Reference)

Acceptor Substrates (KEM-C)

Expression

RNA Expression from Human Protein Atlas
This RNA expression data uses "HPA data" from the Human Protein Atlas. Tissue RNA Expression

data available from v22.proteinatlas.org

Expression (Reference)

Gene Ontology

This page does not indicate all of the enzymatic reaction, and expression of "ST6GALNAC4".