ST6GALNAC4

Last Update:2016-01-29

ST6GALNAC4あるいはN-アセチルガラクトサミニドα-2,6-シアリルトランスフェラーゼ4は、シアリル酸をCMPシアリル酸からアシアロフェチュインを除くフェチュインなどの糖タンパク質上のNeuAcα2→3Galβ1→3GalNAc-R構造に転移する。ST6GALNAC4はSIAT7D やSIAT3Cとも知られる。ST6GALNAC4は、O-グリカンのジシアリル-T構造NeuAcα2→3Galβ1→3(NeuAcα2→6)GalNAc-Ser/Thrを合成する酵素候補である。

Keyword: シアリル-T ,  ジシアリル-T

CMP-Neu5Ac
JCGG-STR025535
GlyTouCan: G65562ZE
GlyCosmos Glycans: G65562ZE
JCGG-STR026341
GlyTouCan: G01614ZM
GlyCosmos Glycans: G01614ZM

CMP-Neu5Ac
JCGG-STR025535
GlyTouCan: G65562ZE
GlyCosmos Glycans: G65562ZE
JCGG-STR026341
GlyTouCan: G01614ZM
GlyCosmos Glycans: G01614ZM

Sialyltransferase


GGDB Symbol ST6GALNAC4    Alias
DesignationGalNAc alpha-2, 6-sialyltransferase IV
OrganismHomo sapiens
GeneID 27090
HGNC ST6GALNAC4 (17846)
mRNA NM_014403
map9q34
Protein NP_055218
EC# 2.4.99.7   
CAZy GT29   
GlyCosmos Glycogenes ST6GALNAC4
OMIM 606378
Disease name
GDGDB
Human Protein Atlas ENSG00000136840
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Orthologous Gene

Acceptor Substrates (Reference)

Acceptor Substrates (KEM-C)

Expression

RNA Expression from Human Protein Atlas
This RNA expression data uses "HPA data" from the Human Protein Atlas. Tissue RNA Expression

data available from v22.proteinatlas.org

Expression (Reference)

Gene Ontology

This page does not indicate all of the enzymatic reaction, and expression of "ST6GALNAC4".