ST8SIA5

Last Update:2016-01-29

ST8SIA5あるいはST8 α-N-アセチルノイラミニドα-2,8-シアリルトランスフェラーゼ5は、CMPシアリル酸からシアリル酸を、糖脂質上のNeuAcα2→3-RおよびNeuAcα2→8-R構造に転移し2,8-結合でジシアル酸からオリゴシアル酸を合成する。ST8SIA5はSIAT8EあるいはST8Sia-Vとも知られる。GM1b、GD1a、GT1bおよびGD3はST8SIA5の良い受容体分子であり、ST8SIA5がSAT-IIIおよびSAT-Vの遺伝子候補であることが示唆される。

Keyword:

CMP-Neu5Ac
JCGG-STR005131
GlyTouCan: G40183QN
GlyCosmos Glycans: G40183QN
JCGG-STR004466
GlyTouCan: G18625KA
GlyCosmos Glycans: G18625KA

CMP-Neu5Ac
JCGG-STR024659
GlyTouCan: G46677TE
GlyCosmos Glycans: G46677TE
JCGG-STR027119
GlyTouCan: G68110IF
GlyCosmos Glycans: G68110IF

CMP-Neu5Ac
JCGG-STR003473
GlyTouCan: G98544DH
GlyCosmos Glycans: G98544DH
JCGG-STR026373
GlyTouCan: G93899SO
GlyCosmos Glycans: G93899SO

Sialyltransferase


GGDB Symbol ST8SIA5    Alias
DesignationST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
OrganismHomo sapiens
GeneID 29906
HGNC ST8SIA5 (17827)
mRNA NM_013305
map18q21.1
Protein NP_037437
EC#    
CAZy GT29   
GlyCosmos Glycogenes ST8SIA5
OMIM 607162
Disease name
GDGDB
Human Protein Atlas ENSG00000101638
Open ALL Close ALL

Orthologous Gene

Acceptor Substrates (Reference)

Acceptor Substrates (KEM-C)

Expression

RNA Expression from Human Protein Atlas
This RNA expression data uses "HPA data" from the Human Protein Atlas. Tissue RNA Expression

data available from v22.proteinatlas.org

Expression (Reference)

Gene Ontology

This page does not indicate all of the enzymatic reaction, and expression of "ST8SIA5".