GGDB:

B3GALT6はbeta-1,3-galactosyltransferase 6をコードする。本酵素は、非還元末端のGallβ-をアクセプター基質として、β1,3結合でGalを転移し、Galβ1,3Galβ-を合成する。この構造は、へパラン硫酸やコンドロイチン硫酸などのグリコサミノグリカンとプロテオグリカンコアタンパク質間のリンケージ構造 (GlcAβ1-3Galβ1-3Galβ1-4Xyl-O-Ser/Thr)に存在する。

Keyword: へパラン硫酸 , グリコサミノグリカン , コンドロイチン硫酸

	UDP-Gal
JCGG-STR018505 GlyTouCan: G78098IA GlyCosmos Glycans: G78098IA		JCGG-STR028206 GlyTouCan: G87877ES GlyCosmos Glycans: G87877ES

Galactosyltransferase

GGDB Symbol

B3GALT6 Alias

Designation

beta 1,3-galactosyltransferase 6

Organism

Homo sapiens

GeneID

126792

HGNC

B3GALT6 (17978)

mRNA

NM_080605

map

1p36.33

Protein

NP_542172

EC#

2.4.1.134

CAZy

GT31

GlyCosmos Glycogenes

B3GALT6

OMIM

615291

Disease name

GDGDB

Human Protein Atlas

ENSG00000176022

Mus musculus

mRNA	NM_080445
Protein	NP_536693
MGI	77575

Rattus norvegicus

mRNA	NM233721
Protein	XP_233721

Caenorhabditis elegans

mRNA	NM_061993
Protein	NP_494394

Drosophila melanogaster

mRNA	NM_136555
Protein	NP_610399

J. Biol. Chem. 2001-12-01 ;276(51):48189-95.

Biosynthesis of the linkage region of glycosaminoglycans: cloning and activity of galactosyltransferase II, the sixth member of the beta 1,3-galactosyltransferase family (beta 3GalT6).

Bai X. et al. PMID:11551958 Refer to: Table 1.

DONOR : UDP-Gal

Glc	Man	Gal	GlcNAc	GalNAc	Fuc	Xyl	Neu5Ac	Neu5Gc	GlcA	IdoA	GlcN

Substrate Transferred

	JCGG-STR018505 GlyTouCan: G78098IA GlyCosmos Glycans: G78098IA	UDP-Gal	JCGG-STR028206 GlyTouCan: G87877ES GlyCosmos Glycans: G87877ES

	JCGG-STR031555 GlyTouCan: G65889KE GlyCosmos Glycans: G65889KE	UDP-Gal	JCGG-STR004799 GlyTouCan: G95894VW GlyCosmos Glycans: G95894VW

	JCGG-STR025711 GlyTouCan: G00031MO GlyCosmos Glycans: G00031MO	UDP-Gal	JCGG-STR026327 GlyTouCan: G70693FX GlyCosmos Glycans: G70693FX

	JCGG-STR013782 GlyTouCan: G00055MO GlyCosmos Glycans: G00055MO	UDP-Gal	JCGG-STR031570 GlyTouCan: G35116BF GlyCosmos Glycans: G35116BF

	JCGG-STR004799 GlyTouCan: G95894VW GlyCosmos Glycans: G95894VW	UDP-Gal	JCGG-STR014157 GlyTouCan: G59103JC GlyCosmos Glycans: G59103JC

Substrate Not Transferred

	JCGG-STR031571 GlyTouCan: G16579HJ GlyCosmos Glycans: G16579HJ

	JCGG-STR031555 GlyTouCan: G65889KE GlyCosmos Glycans: G65889KE

	JCGG-STR025718 GlyTouCan: G57321FI GlyCosmos Glycans: G57321FI

	JCGG-STR025718 GlyTouCan: G57321FI GlyCosmos Glycans: G57321FI

	JCGG-STR021541 GlyTouCan: G00056MO GlyCosmos Glycans: G00056MO

	JCGG-STR004754 GlyTouCan: G33476GF GlyCosmos Glycans: G33476GF

	JCGG-STR007097 GlyTouCan: G51379UR GlyCosmos Glycans: G51379UR

RNA Expression from Human Protein Atlas

This RNA expression data uses "HPA data" from the Human Protein Atlas. Tissue RNA Expression

data available from v22.proteinatlas.org

J. Biol. Chem. 2001-12-01 ;276(51):48189-95.

Biosynthesis of the linkage region of glycosaminoglycans: cloning and activity of galactosyltransferase II, the sixth member of the beta 1,3-galactosyltransferase family (beta 3GalT6).

Bai X. et al. PMID:11551958

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B3GALT6

Galactosyltransferase

Orthologous Gene

Mus musculus

Rattus norvegicus

Caenorhabditis elegans

Drosophila melanogaster

Acceptor Substrates (Reference)

Biosynthesis of the linkage region of glycosaminoglycans: cloning and activity of galactosyltransferase II, the sixth member of the beta 1,3-galactosyltransferase family (beta 3GalT6).

DONOR : UDP-Gal

Substrate Transferred

Substrate Not Transferred

Acceptor Substrates (KEM-C)

Expression

Expression (Reference)

Biosynthesis of the linkage region of glycosaminoglycans: cloning and activity of galactosyltransferase II, the sixth member of the beta 1,3-galactosyltransferase family (beta 3GalT6).

Gene Ontology