GALNT9

Last Update:2015-10-27

The first step in mucin-type O-glycosylation is catalyzed by UDP N-acetylgalactosamine (GalNAc):polypeptide GalNAc transferases (EC 2.4.1.41). Each member of this large enzyme family has a unique substrate specificity and expression profile. GALNT9 belongs to a subfamily of GALNTs found only in vertebrates. Other members of this subfamily include GALNT8 (606250), GALNT19 (615137), and GALNT18 (615136). Due to critical substitutions in a conserved catalytic motif, members of this subfamily lack significant GalNAc transferase activity (Li et al., 2012). ###Copied from OMIM###

Keyword: O-glycan ,  Tn-antigen ,  mucin ,  tumor marker

UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase


GGDB Symbol GALNT9    Alias
DesignationUDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9
OrganismHomo sapiens
GeneID 50614
HGNC GALNT9 (4131)
mRNA AB040672
map12q24.33
Protein BAB13699
EC# 2.4.1.41   
CAZy GT27   
GlyCosmos Glycogenes GALNT9
OMIM 606251
Disease name
GDGDB
Human Protein Atlas ENSG00000182870
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Orthologous Gene

Acceptor Substrates (Reference)

Acceptor Substrates (KEM-C)

Expression

RNA Expression from Human Protein Atlas
This RNA expression data uses "HPA data" from the Human Protein Atlas. Tissue RNA Expression

data available from v22.proteinatlas.org

Expression (Reference)

Gene Ontology

This page does not indicate all of the enzymatic reaction, and expression of "GALNT9".