GALNT12

Last Update:2015-10-27

This enzyme catalyzes the GalNAc transfer from UDP-GalNAc to Ser or Thr residue in the protein. The product is GalNAc-alpha-O-Ser/Thr structure, so-called Tn-antigen, which is the base structure of mucin type O-glycan. The acceptor substrate (protein) is typically Mucin. GALNT12 is the twelfth member of this enzyme family. This isozyme is expressed in digestive organ.

Keyword: O-glycan ,  Tn-antigen ,  mucin ,  tumor marker
HO-Ser/Thr
UDP-GalNAc 		GalNAc(alpha1-O)-Ser/Thr

UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase


GGDB Symbol GALNT12    Alias
DesignationUDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12
OrganismHomo sapiens
GeneID 79695
HGNC GALNT12 (19877)
mRNA AJ132365
map9q22.33
Protein CAC80100
EC# 2.4.1.41   
CAZy GT27   
GlyCosmos Glycogenes GALNT12
OMIM 610290
Disease name
GDGDB
Human Protein Atlas ENSG00000119514
Open ALL Close ALL

Orthologous Gene

Acceptor Substrates (Reference)

Acceptor Substrates (KEM-C)

Expression

RNA Expression from Human Protein Atlas
This RNA expression data uses "HPA data" from the Human Protein Atlas. Tissue RNA Expression

data available from v22.proteinatlas.org

Expression (Reference)

Gene Ontology

This page does not indicate all of the enzymatic reaction, and expression of "GALNT12".