GALNT14

Last Update:2015-10-27

This enzyme catalyzes the GalNAc-transfer from UDP-GalNAc to Ser or Thr residue in the protein. The product is GalNAc-alpha-O-Ser/Thr structure, so-called Tn-antigen, which is the base structure of mucin type O-glycan. The acceptor substrate (protein) is typically Mucin. GALNT14 is the 14th member of this enzyme family. This isozyme may be involved in the O-glycosylation in kidney.

Keyword: O-glycan ,  Tn-antigen ,  mucin ,  tumor marker
HO-Ser/Thr
UDP-GalNAc 		GalNAc(alpha1-O)-Ser/Thr

UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase


GGDB Symbol GALNT14    Alias
DesignationUDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14
OrganismHomo sapiens
GeneID 79623
HGNC GALNT14 (22946)
mRNA AY358758
map2p23.1
Protein AAQ89118
EC# 2.4.1.41   
CAZy GT27   
GlyCosmos Glycogenes GALNT14
OMIM 608225
Disease name
GDGDB
Human Protein Atlas ENSG00000158089
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Orthologous Gene

Acceptor Substrates (Reference)

Acceptor Substrates (KEM-C)

Expression

RNA Expression from Human Protein Atlas
This RNA expression data uses "HPA data" from the Human Protein Atlas. Tissue RNA Expression

data available from v22.proteinatlas.org

Expression (Reference)

Gene Ontology

This page does not indicate all of the enzymatic reaction, and expression of "GALNT14".