B4GALNT4

Last Update:2016-02-09

β1,4-N-acetylgalactosaminyltransferase- IV (B4GALNT4)はUDP-GalNAcのGalNAcをGlcNAcβ-Rに転移しN-およびO-グリカン上のN,N'-diacetyllactosamine, GalNAcβ1→4GlcNAc (LacdiNAc)を合成する。B4GALNT4はB4GalNac-T4およびNGalNAc-T1としても知られる。B4GALNT3とB4GALNT4はともにルトロピン(LH)、サイロトロピン(TSH)、zona pellucida 3(ZP3)を含む様々な糖タンパク質および細胞外基質糖タンパク質でLacdiNAc構造を合成する。これら二つの糖転移酵素の発現パターンは異なっている。

Keyword:

UDP-GalNAc
JCGG-STR008276
GlyTouCan: G49108TO
GlyCosmos Glycans: G49108TO
JCGG-STR029533
GlyTouCan: G00057MO
GlyCosmos Glycans: G00057MO

N-Acetylgalactosaminyltransferase


GGDB Symbol B4GALNT4    Alias
Designationbeta 1,4 N-acetylgalactosaminyltransferase 4
OrganismHomo sapiens
GeneID 338707
HGNC B4GALNT4 (26315)
mRNA NM_178537
map11p15.5
Protein NP_848632
EC#    
CAZy
GlyCosmos Glycogenes B4GALNT4
OMIM
Disease name
GDGDB
Human Protein Atlas ENSG00000182272
Open ALL Close ALL

Orthologous Gene

Acceptor Substrates (Reference)

Acceptor Substrates (KEM-C)

Expression

RNA Expression from Human Protein Atlas
This RNA expression data uses "HPA data" from the Human Protein Atlas. Tissue RNA Expression

data available from v22.proteinatlas.org

Expression (Reference)

Gene Ontology

This page does not indicate all of the enzymatic reaction, and expression of "B4GALNT4".