GCNT4 is a glucosaminyl (N-acetyl) transferase 4, core 2, which transfers GlcNAc from UDP-GlcNAc to the C6 position of GalNAc in core 1 O-glycan structure, synthesizing core 2 structure similar to GCNT1. GCNT4 is also known as C2GNT3. GCNT4 is highly expressed in thymus, suggesting its roles in T-cell development and lymphocyte trafficking.
Keyword:
O-glycan
, core 2
, mucin
, thymus
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JCGG-STR025711
GlyTouCan:
G00031MO
GlyCosmos Glycans:
G00031MO
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JCGG-STR029201
GlyTouCan:
G00033MO
GlyCosmos Glycans:
G00033MO
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N-Acetylglucosaminyltransferase
| GCNT4 Alias | |
| Designation | glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase) |
| Organism | Homo sapiens |
| GeneID | 51301 |
| HGNC | GCNT4 (17973) |
| mRNA | NM_016591 |
| map | 5q12 |
| Protein | NP_057675 |
| EC# | |
| CAZy | GT14 |
| GlyCosmos Glycogenes | GCNT4 |
| OMIM | 616782 |
| GDGDB | |
| Human Protein Atlas | ENSG00000176928 |
Mus musculus
Rattus norvegicus
