MGAT5 (β1,4-N-Acetylglucosaminyltransferase-V) transfers GlcNAc to β1-6 on mannose of the GlcNAcβ1-2Manα1-6 structure (GlcNAcβ1-2Manα1-6Manβ1-R). GnT-V expresses in most of human and rodent tissues, while GnT-Vb mainly localizes in neural tissue and testes. GnT-Vb can synthesize GlcNAcβ1,6Man on both N- and O-glycans.
Keyword:
GNT-V
, GNT5
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JCGG-STR009224
GlyTouCan:
G39213VZ
GlyCosmos Glycans:
G39213VZ
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JCGG-STR009323
GlyTouCan:
G10219AA
GlyCosmos Glycans:
G10219AA
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N-Acetylglucosaminyltransferase
| MGAT5 Alias | |
| Designation | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase |
| Organism | Homo sapiens |
| GeneID | 4249 |
| HGNC | MGAT5 (7049) |
| mRNA | NM_002410 |
| map | 2q21 |
| Protein | NP_002401 |
| EC# | 2.4.1.155 |
| CAZy | GT18 |
| GlyCosmos Glycogenes | MGAT5 |
| OMIM | 601774 |
| GDGDB | |
| Human Protein Atlas | ENSG00000152127 |
Mus musculus
Rattus norvegicus
Caenorhabditis elegans
