ALG5 encodes dolichol-phosphate glucosyltransferase that is involved in the synthesis of lipid-linked oligosaccharides in the endoplasmic reticulum. UDP-glucose and dolichol-phosphate are used as donor and acceptor substrates, respectively.
Keyword:
dolichol-phosphate-glucose
|
dolichol-phosphate
|
UDP-Glc
|
dolichol-phosphate-glucose
|
|
|
|
|
Glucosyltransferase
| GGDB Symbol |
ALG5
Alias
|
HGNC Symbol
|
: |
ALG5
|
|
clone name
|
: |
RP11-421P11.2
|
|
unknown
|
: |
bA421P11.2
|
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| Designation | asparagine-linked glycosylation 5, dolichol-phosphate beta-glucosyltransferase homolog (S. cerevisiae) |
| Organism | Homo sapiens |
| GeneID |
29880
|
| HGNC |
ALG5
(20266)
|
| mRNA |
NM_013338
|
| map | 13q13.3 |
| Protein |
NP_037470
|
| EC# |
2.4.1.117
|
| CAZy |
GT2
|
| GlyCosmos Glycogenes |
ALG5
|
| OMIM |
604565
|
| Disease name |
|
| GDGDB |
|
| Human Protein Atlas |
ENSG00000120697
|
Proc. Natl. Acad. Sci. U.S.A. 1999-06-01 ;96(12):6982-7.
A mutation in the human ortholog of the Saccharomyces cerevisiae ALG6 gene causes carbohydrate-deficient glycoprotein syndrome type-Ic.
Imbach T. et al.
PMID:10359825
brainheartkidneyliverpancreasplacentaskeletal muscle
This page does not indicate all of the enzymatic reaction, and expression of "ALG5".