ALG9

Last Update:2016-08-10

ALG9 encodes alpha-1,2-mannosyltransferase that is involved in the synthesis of lipid-linked oligosaccharides in the endoplasmic reticulum. Dolichol-phosphate-mannose is used for the donor substrate. ALG9 complements the defect of the yeast alg9 mutant. Mutation of ALG9 is associated with congenital disorder of glycosylation type 1L.

Keyword: congenital disorders of glycosylation ,  lipid-linked oligosaccharide

Dol-P-Man
JCGG-STR000132
GlyTouCan: G44865OQ
GlyCosmos Glycans: G44865OQ
JCGG-STR000133
GlyTouCan: G72103RY
GlyCosmos Glycans: G72103RY

Dol-P-Man
JCGG-STR000134
GlyTouCan: G48148JS
GlyCosmos Glycans: G48148JS
JCGG-STR028843
GlyTouCan: G39578OU
GlyCosmos Glycans: G39578OU

Mannosyltransferases


GGDB Symbol ALG9    Alias
DesignationDol-P-Mannose:Man6GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase, Dol-P-Mannose:Man8GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase
OrganismHomo sapiens
GeneID 79796
HGNC ALG9 (15672)
mRNA NM_024740
map11q22-23
Protein NP_079016
EC#    
CAZy
GlyCosmos Glycogenes ALG9
OMIM 606941
Disease name CDG Il ,  Congenital Disorder of Glycosylation type Il
GDGDB CON00354   
Human Protein Atlas ENSG00000086848
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Orthologous Gene

Acceptor Substrates (Reference)

Acceptor Substrates (KEM-C)

Expression

RNA Expression from Human Protein Atlas
This RNA expression data uses "HPA data" from the Human Protein Atlas. Tissue RNA Expression

data available from v22.proteinatlas.org

Expression (Reference)

Gene Ontology

This page does not indicate all of the enzymatic reaction, and expression of "ALG9".