ALG9

Last Update:2016-08-10

ALG9は小胞体での脂質結合型糖鎖の合成に関わるアルファ1,2マンノース転移酵素をコードする。ドリコールリン酸マンノースが供与体基質として用いられる。ALG9は酵母のalg9欠損変異を相補する。ALG9の変異は先天性グリコシル化異常症１L型に関連する。

Keyword: 先天性グリコシル化異常症 ,  脂質結合型糖鎖

Dol-P-Man
JCGG-STR000132
GlyTouCan: G44865OQ
GlyCosmos Glycans: G44865OQ
JCGG-STR000133
GlyTouCan: G72103RY
GlyCosmos Glycans: G72103RY

Dol-P-Man
JCGG-STR000134
GlyTouCan: G48148JS
GlyCosmos Glycans: G48148JS
JCGG-STR028843
GlyTouCan: G39578OU
GlyCosmos Glycans: G39578OU

Mannosyltransferases


GGDB Symbol ALG9    Alias
DesignationDol-P-Mannose:Man6GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase, Dol-P-Mannose:Man8GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase
OrganismHomo sapiens
GeneID 79796
HGNC ALG9 (15672)
mRNA NM_024740
map11q22-23
Protein NP_079016
EC#    
CAZy
GlyCosmos Glycogenes ALG9
OMIM 606941
Disease name 先天性糖鎖異常症Il型
GDGDB CON00354   
Human Protein Atlas ENSG00000086848
Open ALL Close ALL

Orthologous Gene

Acceptor Substrates (Reference)

Acceptor Substrates (KEM-C)

Expression

RNA Expression from Human Protein Atlas
This RNA expression data uses "HPA data" from the Human Protein Atlas. Tissue RNA Expression

data available from v22.proteinatlas.org

Expression (Reference)

Gene Ontology

This page does not indicate all of the enzymatic reaction, and expression of "ALG9".