B3GAT3 encodes beta-1,3-glucuronyltransferase 3. This enzyme synthesizes GalAβ1,3Galβ- by transferring glucuronic acid (GalA) with a beta 1,3 linkage toward non-reducing terminal Galβ- as an acceptor substrate. This structure is found in the linkage structure (GlcAβ1-3Galβ1-3Galβ1-4Xyl-O-Ser/Thr) between glycosaminoglycans such as heparan sulfate and chondroitin sulfate and proteoglycan core proteins.
Keyword:
Chondroitin sulfate
, Heparan sulfate
, glycosaminoglycan
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JCGG-STR028206
GlyTouCan:
G87877ES
GlyCosmos Glycans:
G87877ES
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JCGG-STR027487
GlyTouCan:
G14371GV
GlyCosmos Glycans:
G14371GV
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Glucuronyltransferase
| B3GAT3 Alias | |
| Designation | beta-1,3-glucuronyltransferase 3 |
| Organism | Homo sapiens |
| GeneID | 26229 |
| HGNC | B3GAT3 (923) |
| mRNA | NM_012200 |
| map | 11q12.3 |
| Protein | NP_036332 |
| EC# | 2.4.1.135 |
| CAZy | GT43 |
| GlyCosmos Glycogenes | B3GAT3 |
| OMIM | 606374 |
| GDGDB | |
| Human Protein Atlas | ENSG00000149541 |
Mus musculus
Rattus norvegicus
Drosophila melanogaster
