CSGlcA-T (CHPF2) encodes chondroitin sulfate glucuronyltransferase (chondroitin polymerizing factor 2), which is involved in the biosynthesis of chondroitin sulfate. CSGlcA-T (CHPF2) forms a complex with CHSY1, CHPF, and CHSY3 and is responsible for the elongation reaction of chondroitin chains. In vitro, CSGlcA-T (CHPF2) does not show GalNAc-transferase activity, but only GlcA-transferase activity.
Keyword:
chondroitin
, chondroitin sulfate
, proteoglycan
Glucuronyltransferase
| CSGlcA-T Alias | |
| Designation | chondroitin sulfate glucuronyltransferase |
| Organism | Homo sapiens |
| GeneID | 54480 |
| HGNC | CHPF2 (29270) |
| mRNA | AB037823 |
| map | 7q36.1 |
| Protein | BAA92640 |
| EC# | 2.4.1.226 |
| CAZy | GT31 |
| GlyCosmos Glycogenes | CSGlcA-T |
| OMIM | 608037 |
| GDGDB | |
| Human Protein Atlas | ENSG00000033100 |
Mus musculus
Rattus norvegicus
