CSGlcA-T |
Last Update:2021-12-17 |
CSGlcA-T (CHPF2) は、chondroitin sulfate glucuronyltransferase (chondroitin polymerizing factor 2)をコードし、GAGの1種であるコンドロイチン硫酸の生合成に関与する。コンドロイチン硫酸は(GalNAcβ1,4GlcAβ1,3)の2糖の繰り返し構造であるが、CSGlcA-T (CHPF2) はCHSY1, CHPF, CHPF2と複合体を形成して、コンドロイチン鎖の伸張反応を担う。CSGlcA-T (CHPF2) はin vitroではGalNAc転移酵素活性を示さず、GlcA転移酵素活性のみを示す。
CSGlcA-T Alias | |
Designation | chondroitin sulfate glucuronyltransferase |
Organism | Homo sapiens |
GeneID | 54480 |
HGNC | CHPF2 (29270) |
mRNA | AB037823 |
map | 7q36.1 |
Protein | BAA92640 |
EC# | 2.4.1.226 |
CAZy | GT31 |
GlyCosmos Glycogenes | CSGlcA-T |
OMIM | 608037 |
GDGDB | |
Human Protein Atlas | ENSG00000033100 |
Glc |
Man |
Gal |
GlcNAc |
GalNAc |
Fuc |
Xyl |
Neu5Ac |
Neu5Gc |
GlcA |
IdoA |
GlcN |
---|
GlyTouCan:
G70907ST
GlyCosmos Glycans:
G70907ST
|
|
GlyTouCan:
G33235EO
GlyCosmos Glycans:
G33235EO
|
|
GlyTouCan:
G97081WO
GlyCosmos Glycans:
G97081WO
|
|
GlyTouCan:
G76533UX
GlyCosmos Glycans:
G76533UX
|
|
GlyTouCan:
G07747BZ
GlyCosmos Glycans:
G07747BZ
|
|
GlyTouCan:
G40723NG
GlyCosmos Glycans:
G40723NG
|
|
data available from v22.proteinatlas.org
adrenal glandsbone marrowbraincerebellumcerebral cortexcolonheartkidneyliverlungmammary glandovarypancreasperipheral blood leukocyteperipheral blood mononuclear cellplacentasmall intestinestomachtestisthymusthyroid glanduterus
N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity |
acetylgalactosaminyltransferase activity |
chondroitin sulfate biosynthetic process |
Golgi cisterna membrane |
Golgi membrane |
integral component of membrane |
membrane |