XYLT2 encodes xylosyltransferase 2. Glycosaminoglycans such as chondroitin sulfate and heparan sulfate are bound to proteoglycan (PG) core proteins via a linkage tetrasaccharide structure (GlcAβ1-3Galβ1-3Galβ1-4Xyl-O-Ser/Thr). XYLT1 is responsible for the first Xyl addition to Ser/Thr of PG core protein.
Keyword:
chondroitin sulfate
, glycosaminoglycan
, heparan sulfate
, proteoglycan
Xylosyltransferase
| XYLT2 Alias | |
| Designation | xylosyltransferase II |
| Organism | Homo sapiens |
| GeneID | 64132 |
| HGNC | XYLT2 (15517) |
| mRNA | NM_022167 |
| map | 17q21.3-17q22 |
| Protein | NP_071450 |
| EC# | 2.4.2.26 |
| CAZy | GT14 |
| GlyCosmos Glycogenes | XYLT2 |
| OMIM | 608125 |
| GDGDB | |
| Human Protein Atlas | ENSG00000015532 |
Mus musculus
Rattus norvegicus
Caenorhabditis elegans