Last Update:2017-12-11

SLC35C1 encodes a GDP-fucose transporter that is localized in the Golgi membrane. It is also known as FUCT1. The encoded protein has multiple membrane-spanning regions. GDP-fucose is transported into the Golgi lumen and used as a glycosyl donor for glycan synthesis. Mutation of SLC35C1 is associated with congenital disorder of glycosylation type 2C.

Keyword: FUCT ,  GDP-fucose ,  congenital disorder of glycosylation ,  nucleotide sugar transporter

Nucleotide Sugar Transporter

GGDB Symbol SLC35C1    Alias
DesignationGDP-fucose transporter
OrganismHomo sapiens
GeneID 55343
HGNC SLC35C1 (20197)
mRNA NM_018389
Protein NP_060859
GlyCosmos Glycogenes SLC35C1
OMIM 605881
Disease name CDGIIc ,  Congenital Disorder of Glycosylation type IIc
GDGDB CON00360   
Human Protein Atlas ENSG00000181830
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Orthologous Gene

Acceptor Substrates (Reference)

Acceptor Substrates (KEM-C)


RNA Expression from Human Protein Atlas
This RNA expression data uses "HPA data" from the Human Protein Atlas. Tissue RNA Expression

data available from

Expression (Reference)

Gene Ontology

This page does not indicate all of the enzymatic reaction, and expression of "SLC35C1".