GGDB:

SLC35A3 encodes a UDP-N-acetylglucosamine (UDP-GlcNAc) transporter that is localized in the Golgi membrane. It is also known as UGTREL2. The encoded protein has multiple membrane-spanning regions. UDP-GlcNAc is transported into the Golgi lumen and used as a glycosyl donor for glycan synthesis.

Keyword: UDP-GlcNAc , UGT , nucleotide sugar transporter

Nucleotide Sugar Transporter

GGDB Symbol

SLC35A3 Alias

Designation

UDP-N-acetylglucosamine transporter

Organism

Homo sapiens

GeneID

23443

HGNC

SLC35A3 (11023)

mRNA

NM_012243

map

1p21

Protein

NP_036375

EC#

CAZy

GlyCosmos Glycogenes

SLC35A3

OMIM

605632

Disease name

GDGDB

Human Protein Atlas

ENSG00000117620

Mus musculus

mRNA	NM_144902
Protein	NP_659151

Rattus norvegicus

mRNA	NM_001012082
Protein	NP_001012082

Caenorhabditis elegans

mRNA	NM_061322
Protein	NP_493723

J. Biochem. 1999-07-01 ;126(1):68-77.

Molecular cloning and functional expression of the human Golgi UDP-N-acetylglucosamine transporter.

Ishida N. et al. PMID:10393322

RNA Expression from Human Protein Atlas

This RNA expression data uses "HPA data" from the Human Protein Atlas. Tissue RNA Expression

data available from v22.proteinatlas.org

Provided by GOA

Function
UDP-N-acetylglucosamine transmembrane transporter activity
protein binding
sugar:proton symporter activity

Process
UDP-N-acetylglucosamine metabolic process
UDP-N-acetylglucosamine transmembrane transport
UDP-N-acetylglucosamine transport
carbohydrate transport
proton transport

Component
Golgi apparatus
Golgi membrane
integral component of membrane

SLC35A3

Nucleotide Sugar Transporter

Orthologous Gene

Mus musculus

Rattus norvegicus

Caenorhabditis elegans

Acceptor Substrates (Reference)

Molecular cloning and functional expression of the human Golgi UDP-N-acetylglucosamine transporter.

Acceptor Substrates (KEM-C)

Expression

Expression (Reference)

Gene Ontology