SLC35D1 encodes a UDP-glucuronic acid (UDP-GlcA)/UDP-N-acetylgalactosamine (UDP-GalNAc) transporter with dual substrate specificity that is localized in the Golgi membrane. It is also known as UGTREL7. The encoded protein has multiple membrane-spanning regions. UDP-GlcA and UDP-GalNAc are transported into the Golgi lumen and used as a glycosyl donor for glycan synthesis.
Keyword:
UDP-N-acetylgalactosamine
, UDP-glucuronic acid
, UGT
, nucleotide sugar transporter
Nucleotide Sugar Transporter
| SLC35D1 Alias | |
| Designation | UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter |
| Organism | Homo sapiens |
| GeneID | 23169 |
| HGNC | SLC35D1 (20800) |
| mRNA | NM_015139 |
| map | 1p32-p31 |
| Protein | NP_055954 |
| EC# | |
| CAZy | |
| GlyCosmos Glycogenes | SLC35D1 |
| OMIM | 610804 |
| GDGDB | |
| Human Protein Atlas | ENSG00000116704 |
Mus musculus
Rattus norvegicus
Caenorhabditis elegans
Drosophila melanogaster