Last Update:2017-12-11

SLC35A1 encodes a CMP-sialic acid transporter that is localized in the Golgi membrane. It is also known as CST. The encoded protein has multiple membrane-spanning regions. CMP-sialic acid is transported into the Golgi lumen and used as a glycosyl donor for glycan synthesis. Mutation of SLC35A1 is associated with congenital disorder of glycosylation type 2F.

Keyword: CMP-silaic acid ,  CST ,  congenital disorder of glycosylation ,  nucleotide sugar transporter

Nucleotide Sugar Transporter

GGDB Symbol SLC35A1    Alias
DesignationCMP-sialic acid transporter
OrganismHomo sapiens
GeneID 10559
HGNC SLC35A1 (11021)
mRNA NM_006416
Protein NP_006407
GlyCosmos Glycogenes SLC35A1
OMIM 605634
Disease name
Human Protein Atlas ENSG00000164414
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Orthologous Gene

Acceptor Substrates (Reference)

Acceptor Substrates (KEM-C)


RNA Expression from Human Protein Atlas
This RNA expression data uses "HPA data" from the Human Protein Atlas. Tissue RNA Expression

data available from

Expression (Reference)

Gene Ontology

This page does not indicate all of the enzymatic reaction, and expression of "SLC35A1".