SLC35A1 encodes a CMP-sialic acid transporter that is localized in the Golgi membrane. It is also known as CST. The encoded protein has multiple membrane-spanning regions. CMP-sialic acid is transported into the Golgi lumen and used as a glycosyl donor for glycan synthesis. Mutation of SLC35A1 is associated with congenital disorder of glycosylation type 2F.
Keyword:
CMP-silaic acid
, CST
, congenital disorder of glycosylation
, nucleotide sugar transporter
Nucleotide Sugar Transporter
| SLC35A1 Alias | |
| Designation | CMP-sialic acid transporter |
| Organism | Homo sapiens |
| GeneID | 10559 |
| HGNC | SLC35A1 (11021) |
| mRNA | NM_006416 |
| map | 6q15 |
| Protein | NP_006407 |
| EC# | |
| CAZy | |
| GlyCosmos Glycogenes | SLC35A1 |
| OMIM | 605634 |
| GDGDB | |
| Human Protein Atlas | ENSG00000164414 |
Mus musculus
Rattus norvegicus