GXYLT2

Last Update:2016-12-15

GXYLT2 encodes (UDP-xylose: beta-glucoside alpha1,3-xylosyltransferase 2), which has activity to transfer xyloseto the O-linked glucose on the epidermal growth factor (EGF) domain of Notch protein (related to Xyla1-3Glc-Ser synthesis). In mammals, the O-linked glucose structure consists of trisaccharide (Xyla1-3Xyla1-3Glc-Ser), but this enzyme transfers the first xylose only, and the second xylose is synthesized by another enzyme (refer to XXYLT1).

Keyword: EGF(epidermal growth factor) domain ,  O-linked glucose ,  alpha1,3-xylosyltransferase

UDP-Xyl
JCGG-STR031569
GlyTouCan: G71142DF
GlyCosmos Glycans: G71142DF
JCGG-STR031321
GlyTouCan: G01629YL
GlyCosmos Glycans: G01629YL


GGDB Symbol GXYLT2    Alias
Designationglucoside xylosyltransferase 2
OrganismHomo sapiens
GeneID 727936
HGNC GXYLT2 (33383)
mRNA NM_001080393
map
Protein NP_001073862
EC#    
CAZy
GlyCosmos Glycogenes GXYLT2
OMIM 613322
Disease name
GDGDB
Human Protein Atlas ENSG00000172986
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Orthologous Gene

Acceptor Substrates (Reference)

Acceptor Substrates (KEM-C)

Expression

RNA Expression from Human Protein Atlas
This RNA expression data uses "HPA data" from the Human Protein Atlas. Tissue RNA Expression

data available from v22.proteinatlas.org

Expression (Reference)

Gene Ontology

This page does not indicate all of the enzymatic reaction, and expression of "GXYLT2".