GXYLT2 encodes (UDP-xylose: beta-glucoside alpha1,3-xylosyltransferase 2), which has activity to transfer xyloseto the O-linked glucose on the epidermal growth factor (EGF) domain of Notch protein (related to Xyla1-3Glc-Ser synthesis). In mammals, the O-linked glucose structure consists of trisaccharide (Xyla1-3Xyla1-3Glc-Ser), but this enzyme transfers the first xylose only, and the second xylose is synthesized by another enzyme (refer to XXYLT1).
Keyword:
EGF(epidermal growth factor) domain
, O-linked glucose
, alpha1,3-xylosyltransferase
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JCGG-STR031569
GlyTouCan:
G71142DF
GlyCosmos Glycans:
G71142DF
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JCGG-STR031321
GlyTouCan:
G01629YL
GlyCosmos Glycans:
G01629YL
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| GXYLT2 Alias | |
| Designation | glucoside xylosyltransferase 2 |
| Organism | Homo sapiens |
| GeneID | 727936 |
| HGNC | GXYLT2 (33383) |
| mRNA | NM_001080393 |
| map | |
| Protein | NP_001073862 |
| EC# | |
| CAZy | |
| GlyCosmos Glycogenes | GXYLT2 |
| OMIM | 613322 |
| GDGDB | |
| Human Protein Atlas | ENSG00000172986 |
