ALG11 encodes alpha-1,2-mannosyltransferase that is involved in the synthesis of lipid-linked oligosaccharides in the endoplasmic reticulum. Two mannose residues are incorporated sequentially by this enzyme. GDP-mannose is used for the donor substrate. Mutation of ALG11 is associated with congenital disorder of glycosylation type 1P.
Keyword:
congenital disorders of glycosylation
, lipid-linked oligosaccharide
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JCGG-STR026209
GlyTouCan:
G43547MI
GlyCosmos Glycans:
G43547MI
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JCGG-STR000131
GlyTouCan:
G35257SQ
GlyCosmos Glycans:
G35257SQ
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JCGG-STR000131
GlyTouCan:
G35257SQ
GlyCosmos Glycans:
G35257SQ
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JCGG-STR028026
GlyTouCan:
G59406KS
GlyCosmos Glycans:
G59406KS
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Mannosyltransferases
| ALG11 Alias | |
| Designation | asparagine-linked glycosylation 11 homolog (S. cerevisiae, alpha-1,2-mannosyltransferase) |
| Organism | Homo sapiens |
| GeneID | 440138 |
| HGNC | ALG11 (32456) |
| mRNA | NM_001004127 |
| map | 13q14.3-21.1 |
| Protein | NP_001004127 |
| EC# | |
| CAZy | |
| GlyCosmos Glycogenes | ALG11 |
| OMIM | 613666 |
| GDGDB | |
| Human Protein Atlas | ENSG00000253710 |
Mus musculus
Rattus norvegicus
Caenorhabditis elegans
Drosophila melanogaster
Saccharomyces cerevisiae