ALG13

Last Update:2016-08-10

ALG13 encodes the catalytic subunit of UDP-N-acetylglucosamine transferase that is involved in the synthesis of lipid-linked oligosaccharides in the endoplasmic reticulum. ALG13 protein associates with ALG14 protein to form bipartite UDP-N-acetylglucosamine transferase required for the second step of N-linked glycosylation. Co-expression of ALG13 and ALG14 functionally complements the defect of either alg13 or alg14 mutant in yeast. Mutation of ALG13 is associated with congenital disorder of glycosylation type 1s.

Keyword: congenital disorders of glycosylation ,  lipid-linked oligosaccharide

UDP-GlcNAc
JCGG-STR008690
GlyTouCan: G68544GH
GlyCosmos Glycans: G68544GH
JCGG-STR008492
GlyTouCan: G05026ZL
GlyCosmos Glycans: G05026ZL

N-Acetylglucosaminyltransferase


GGDB Symbol ALG13    Alias
Designationglycosyltransferase 28 domain containing 1
OrganismHomo sapiens
GeneID 79868
HGNC ALG13 (30881)
mRNA NM_018466
mapXq23
Protein NP_060936
EC# 2.4.1.141   
CAZy
GlyCosmos Glycogenes ALG13
OMIM 300776
Disease name
GDGDB
Human Protein Atlas ENSG00000101901
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Orthologous Gene

Acceptor Substrates (Reference)

Acceptor Substrates (KEM-C)

Expression

RNA Expression from Human Protein Atlas
This RNA expression data uses "HPA data" from the Human Protein Atlas. Tissue RNA Expression

data available from v22.proteinatlas.org

Expression (Reference)

Gene Ontology

This page does not indicate all of the enzymatic reaction, and expression of "ALG13".