SLC35B4 encodes a UDP-xylose/UDP-N-acetylgalactosamine transporter with dual substrate specificity that is localized in the Golgi membrane. It is also known as YEA4. The encoded protein has multiple membrane-spanning regions. UDP-xylose and UDP-N-acetylglucosamine are transported into the Golgi lumen and used as a glycosyl donor for glycan synthesis.
Keyword:
UDP-N-acetylglucosamine
, UDP-xylose
, YEA4
, nucleotide sugar transporter
Nucleotide Sugar Transporter
| SLC35B4 Alias | |
| Designation | UDP-Xylose/N-Acetylglucosamine transporter |
| Organism | Homo sapiens |
| GeneID | 84912 |
| HGNC | SLC35B4 (20584) |
| mRNA | NM_032826 |
| map | 7q33 |
| Protein | NP_116215 |
| EC# | |
| CAZy | |
| GlyCosmos Glycogenes | SLC35B4 |
| OMIM | 610923 |
| GDGDB | |
| Human Protein Atlas | ENSG00000205060 |
Mus musculus
Rattus norvegicus
Caenorhabditis elegans
Drosophila melanogaster
Saccharomyces cerevisiae