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HO-Ser/Thr GalNAc(alpha1-O)-Ser/Thr
This enzyme catalyzes the GalNAc-transfer from UDP-GalNAc to Ser or Thr residue in the protein. The product is GalNAc-alpha-O-Ser/Thr structure, so-called Tn-antigen, which is the base structure of mucin type O-glycan. The acceptor substrate (protein) is typically Mucin. GALNT14 is the 14th member of this enzyme family. This isozyme may be involved in the O-glycosylation in kidney.
O-glycan Tn-antigen mucin tumor marker

UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase

GGDB SymbolGALNT14
Alias GALNT15, FLJ12691, FLJ13977, GalNac-T10, GalNac-T14    details
DesignationUDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14
OrganismHomo sapiens
GeneID 79623
HGNC 22946
mRNA AY358758       (CDS)
Protein AAQ89118       (CDS)
map2p23.1
EC# 2.4.1.41   
CAZy GT27   
OMIM 608225   
This page does not indicate all of the enzymatic reaction, and expression of "GALNT14".