FUT1

JCGG-STR000334		JCGG-STR026492

JCGG-STR021541		JCGG-STR021875

JCGG-STR013782		JCGG-STR002937

This gene encodes α1,2-fucossyltransferase 1 (FUT1). In the ABO blood type, O antigen (H antigen) is synthesized by the α1,2-FUT group, which transfers fucose to the Gal residue of Galβ1-3/4GlcNAcβ-R structure with α1-2-linkage. This enzyme is one of the three enzymes with α1,2-FUT activity known in human. This enzyme is also known as “H enzyme”, and is broadly expressed in organs of entire body such as myeloid cells, nerve tissue, and intestinal epithelium cells. The H enzyme synthesizes the H antigen on erythrocytes. Rare phenotypes (one in several hundred thousand persons) lacking the H enzyme are called Bombay or para-Bombay phenotypes.

Glc	Man	Gal	GlcNAc	GalNAc	Fuc	Xyl	Neu5Ac	Neu5Gc	GlcA	IdoA	GlcN