FUT4

JCGG-STR014685		JCGG-STR027590

JCGG-STR000638		JCGG-STR024242

JCGG-STR027036		JCGG-STR033543

JCGG-STR027036		JCGG-STR031563

JCGG-STR027036		JCGG-STR029404

This gene encodes α1,3-fucosyltransferase 4 (FUT4). Six α1,3-fucosyltransferases (α3FUT): FUT3, FUT4, FUT5, FUT6, FUT7, and FUT9 are known and confirmed that each enzyme has a characteristic substrate specificity in vitro. Except FUT7, these have activity to transfer fucose to GlcNAc of the type 2 lactosamine structure (Galβ1-4GlcNAcβ1-3-R) with α1-3-linkage. FUT4 is related to synthesis of Lewis x (Lex) carbohydrate antigen, one of the Lewis blood group antigens, but not involved in synthesis of sialyl Lewis x (sLex) antigen. FUT4 has activity to transfer fucose from the GlcNAc residue of the reducing end (internal structure) to the non-reducing end (terminal structure) on the oligosaccharide substrates consisting of polylactosamine (poly-N-acetyllactosamine).
CD15 antigen Lewis blood group Lewis x histoblood group antigen

Glc	Man	Gal	GlcNAc	GalNAc	Fuc	Xyl	Neu5Ac	Neu5Gc	GlcA	IdoA	GlcN