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JCGG-STR014685 JCGG-STR027590
JCGG-STR000638 JCGG-STR024242
JCGG-STR027036 JCGG-STR033543
JCGG-STR027036 JCGG-STR031563
JCGG-STR027036 JCGG-STR029404
This gene encodes α1,3-fucosyltransferase 4 (FUT4). Six α1,3-fucosyltransferases (α3FUT): FUT3, FUT4, FUT5, FUT6, FUT7, and FUT9 are known and confirmed that each enzyme has a characteristic substrate specificity in vitro. Except FUT7, these have activity to transfer fucose to GlcNAc of the type 2 lactosamine structure (Galβ1-4GlcNAcβ1-3-R) with α1-3-linkage. FUT4 is related to synthesis of Lewis x (Lex) carbohydrate antigen, one of the Lewis blood group antigens, but not involved in synthesis of sialyl Lewis x (sLex) antigen. FUT4 has activity to transfer fucose from the GlcNAc residue of the reducing end (internal structure) to the non-reducing end (terminal structure) on the oligosaccharide substrates consisting of polylactosamine (poly-N-acetyllactosamine).
CD15 antigen Lewis blood group Lewis x histoblood group antigen


Alias CD15, ELFT, FCT3A, FUC-TIV    details
Designationalpha1,3-fucosyltransferase 4
OrganismHomo sapiens
GeneID 2526
HGNC 4015
mRNA NM_002033       (CDS)
Protein NP_002024       (CDS)
CAZy GT10   
OMIM 104230   
This page does not indicate all of the enzymatic reaction, and expression of "FUT4".