GlycoGene DataBase

JCGGDB Cross-Search JCGGDB Structure Search
|English |日本語
 |  GGDB |  LfDB |  GMDB |  GPDB |
Top  >  GGDB
Open ALL Close ALL

JCGG-STR027036 JCGG-STR033543
This gene encodes α1,3-fucosyltransferase 6 (FUT6). Six α1,3-fucosyltransferases (α3FUT): FUT3, FUT4, FUT5, FUT6, FUT7, and FUT9 are known and confirmed that each enzyme has a characteristic substrate specificity in vitro. FUT6 has activity to transfer fucose to GlcNAc of type-2 lactosamine structure (Galβ1-4GlcNAcβ1-3-R) or sialylated type-2 lactosamine structure (NeuAcα2-3Galβ1-4GlcNAcβ1-3-R) with α1-3-linkage, and related to synthesis of Lewis x (Lex) or sialyl Lewis x (sLex) antigens. FUT6 is known to be related to many type-2 Lewis blood group antigens (i.e. Lea, Lex, Ley, sLea, sLex, and others).
Lewis blood group Lewis x Lewis y histoblood group antigen sialyl Lewis x


Alias FT1A, FLJ40754    details
Designationalpha1,3-fucosyltransferase 6
OrganismHomo sapiens
GeneID 2528
HGNC 4017
mRNA NM_000150       (CDS)
Protein NP_000141       (CDS)
CAZy GT10   
OMIM 136836   
This page does not indicate all of the enzymatic reaction, and expression of "FUT6".