GlycoGene DataBase

JCGGDB Cross-Search JCGGDB Structure Search
|English |日本語
 |  GGDB |  LfDB |  GMDB |  GPDB |
Top  >  GGDB
Open ALL Close ALL

JCGG-STR009224 JCGG-STR004862
JCGG-STR008820 JCGG-STR033546
This gene encodes α1,3-fucosyltransferase 11 (FUT11). In in vitro enzyme activity assay, FUT11 enzyme is reported to transfer α1-3 fucose to GlcNAc on a core structure of N-glycans (Man-GlcNAc-GlcNAc-Asn) and synthesize a core α1-3-fucose structure (Mainly transfers to agalacto N-glycans. The activity is relatively weak to biantennary N-glycans). However, although carrier glycoproteins of N-glycans with the core α1-3-fucose structure are reported in plants and insects, these are not reported in human. The enzyme does not show activity to short lactosamine acceptor substrates (i.e. Lewis x antigen synthetic activity), which are generally used in activity assays.
Lewis blood group Lewis x histoblood group antigen


GGDB SymbolFUT11
Alias MGC33202, MGC119338, MGC119339    details
Designationalpha1,3-fucosyltransferase 11
OrganismHomo sapiens
GeneID 170384
HGNC 19233
mRNA NM_173540       (CDS)
Protein NP_775811       (CDS)
OMIM 616932   
This page does not indicate all of the enzymatic reaction, and expression of "FUT11".