GlycoGene DataBase

JCGGDB Cross-Search JCGGDB Structure Search
|English |日本語
 |  GGDB |  LfDB |  GMDB |  GPDB |
Top  >  GGDB
Open ALL Close ALL

JCGG-STR025711 JCGG-STR025535
ST3GAL1, β-galactoside α-2,3-sialyltransferase 1, catalyzes sialic acid addition to the core 1 O-glycan, Galβ1→3GalNAc→Ser/Thr, which is a major core structure of mucin type O-glycans. ST3GAL1 was formerly known as ST3O or SIAT4A. ST3GAL1-deficient mice and -transgenic mice demonstrated that sialylation of core 1 O-glycan is required for T lymphocytes homeostasis.
CMP-sialic acid GCNT1 core 1 O-glycan sialyl-T antigen thymus


Alias ST3O, SIAT4A, SIATFL, MGC9183, ST3GalIA, Gal-NAc6S, ST3GalA.1    details
DesignationCMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase I
OrganismHomo sapiens
GeneID 6482
HGNC 10862
mRNA NM_003033       (CDS)
Protein NP_003024       (CDS)
CAZy GT29   
OMIM 607187   
This page does not indicate all of the enzymatic reaction, and expression of "ST3GAL1".