GlycoGene DataBase

JCGGDB Cross-Search JCGGDB Structure Search
|English |日本語
 |  GGDB |  LfDB |  GMDB |  GPDB |
Top  >  GGDB
Open ALL Close ALL




JCGG-STR025711 JCGG-STR025535
ST3GAL2, β-galactoside α-2,3-sialyltransferase 2, transfers sialic acid from CMP-sialic acid to the Galβ1→3GalNAc-R as an acceptor substrate, which are found in glycolipids, such as GM1 and GD1b. ST3GAL2 is also known as SIAT4B. ST3GAL2 is highly expressed in mouse brain and ST3GAL2-deficient mice show decrease of GD1a and GT1b.

Sialyltransferase

GGDB SymbolST3GAL2
Alias SIAT4B, ST3GALII, Gal-NAc6S, ST3GalA.2    details
DesignationCMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase II
OrganismHomo sapiens
GeneID 6483
HGNC 10863
mRNA NM_006927       (CDS)
Protein NP_008858       (CDS)
map16q22.1
EC# 2.4.99.4   
CAZy GT29   
OMIM 607188   
This page does not indicate all of the enzymatic reaction, and expression of "ST3GAL2".