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ST8SIA5
JCGG-STR005131 JCGG-STR004466
JCGG-STR024659 JCGG-STR027119
JCGG-STR003473 JCGG-STR026373
ST8SIA5, ST8 α-N-acetylneuraminide α-2,8-sialyltransferase 5, transfers sialic acid from CMP-sialic acid to the NeuAcα2→3-R or NeuAcα2→8-R structure on glycolipids, synthesizing disialic acid to oligo sialic acid by α2,8-linkage. ST8SIA5 is also known as SIAT8E or ST8Sia-V. Good acceptor molecules for ST8SIA5 are GM1b, GD1a, GT1b, and GD3, suggesting ST8SIA5 as a candidate gene for SAT-III and SAT-V.

Sialyltransferase

GGDB SymbolST8SIA5
Alias SIAT8E, ST8Sia V, MGC119670, MGC119671    details
DesignationST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
OrganismHomo sapiens
GeneID 29906
HGNC 17827
mRNA NM_013305       (CDS)
Protein NP_037437       (CDS)
map18q21.1
EC#
CAZy GT29   
OMIM 607162   

Orthologous Gene

Acceptor Substrates (Reference)

Acceptor Substrates (KEM-C)

Expression

Biological Resources
This page does not indicate all of the enzymatic reaction, and expression of "ST8SIA5".