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JCGG-STR008362 JCGG-STR015836
JCGG-STR008276 JCGG-STR021541
JCGG-STR025794 JCGG-STR004625
JCGG-STR026907 JCGG-STR026929
Compared to other β3GalT enzymes, β3GalT5 (B3GALT5) has a synthetic activity for the strongest Type 1 carbohydrate antigen (Galb1-3GlcNAcb1-3-R). β3Gal-T5 was found to be expressed particularly in the gastrointestinal tract, and by the addition of the sialic acid and fucose to the Type 1 carbohydrate antigen, further greatly contributed to the synthesis of the Type 1 carbohydrate antigens, including the CA19-9 (sialyl Lewis a) antigen. In addition, β3GalT5 has a synthetic activity for Galβ1-3GlcNAcβ1-3GalNAc-O-Ser/Thru by the transfer of a galactose to core 3 O-linked glycans and a synthetic activity for carbohydrate conjugates, like Stage Specific Embryonic Antigen-3 (SSEA-3; Galβ1-3GalNAcβ1-3Galβ1-4Galβ1-4Glcβ1-1Cer).
Sialyl Lewis a Stage Specific Embryonic Antigen-3 (SSEA-3) Type 1 antigen


Alias B3T5, GLCT5, B3GalTx, B3GalT-V, beta3Gal-T5    details
Designationbeta 1,3-galactosyltransferase 5
OrganismHomo sapiens
GeneID 10317
HGNC 920
mRNA NM_033171       (CDS)
Protein NP_006048       (CDS)
CAZy GT31   
OMIM 604066   
This page does not indicate all of the enzymatic reaction, and expression of "B3GALT5".