B3GALT5

JCGG-STR008362		JCGG-STR015836

JCGG-STR008276		JCGG-STR021541

JCGG-STR025794		JCGG-STR004625

JCGG-STR026907		JCGG-STR026929

Compared to other β3GalT enzymes, β3GalT5 (B3GALT5) has a synthetic activity for the strongest Type 1 carbohydrate antigen (Galb1-3GlcNAcb1-3-R). β3Gal-T5 was found to be expressed particularly in the gastrointestinal tract, and by the addition of the sialic acid and fucose to the Type 1 carbohydrate antigen, further greatly contributed to the synthesis of the Type 1 carbohydrate antigens, including the CA19-9 (sialyl Lewis a) antigen. In addition, β3GalT5 has a synthetic activity for Galβ1-3GlcNAcβ1-3GalNAc-O-Ser/Thru by the transfer of a galactose to core 3 O-linked glycans and a synthetic activity for carbohydrate conjugates, like Stage Specific Embryonic Antigen-3 (SSEA-3; Galβ1-3GalNAcβ1-3Galβ1-4Galβ1-4Glcβ1-1Cer).
Sialyl Lewis a Stage Specific Embryonic Antigen-3 (SSEA-3) Type 1 antigen

Glc	Man	Gal	GlcNAc	GalNAc	Fuc	Xyl	Neu5Ac	Neu5Gc	GlcA	IdoA	GlcN