B4GALT2

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GG Family

pathway class
- N-glycan
  - ALG1
  - ALG2
  - ALG3
  - ALG5
  - ALG6
  - ALG8
  - ALG9
  - ALG10
  - ALG11
  - ALG12
  - ALG13
  - ALG14
  - B4GALT1
  - B4GALT2
  - B4GALT3
  - B3GNT8
  - B4GALNT2
  - DPAGT1
  - DPM1
  - DPM2
  - DPM3
  - FUT8
  - FUT10
  - MGAT1
  - MGAT2
  - MGAT3
  - MGAT4A
  - MGAT4B
  - MGAT5
  - MGAT5B
  - ST6GAL1
  - ST6GAL2
  - ST8SIA2
  - ST8SIA3
  - ST8SIA4
  - CHST8
  - CHST9
  - UGGT1 (UGCGL1)
  - UGGT2 (UGCGL2)
- O-glycan, mucin-type
  - B3GNT6
  - B4GALT5
  - A4GNT
  - B4GALNT2
  - C1GALT1
  - C1GALT1C1
  - GALNT1
  - GALNT2
  - GALNT3
  - GALNT4
  - GALNT5
  - GALNT6
  - GALNT7
  - GALNT8
  - GALNT9
  - GALNT10
  - GALNT11
  - GALNT12
  - GALNT13
  - GALNT14
  - GALNT15
  - GALNT16
  - GALNT17
  - GALNT18
  - GALNT19
  - GALNT20
  - GCNT1
  - GCNT3
  - GCNT4
  - ST3GAL1
  - ST3GAL2
  - ST6GALNAC1
  - ST6GALNAC2
  - ST8SIA4
  - ST8SIA6
- O-glycan, not mucin-type
  - B3GLCT
  - B3GAT1
  - B3GAT2
  - B4GALT1
  - B4GALT2
  - B4GALT3
  - B4GALT4
  - B3GALNT2
  - CHST10
  - EOGT
  - FKTN
  - FKRP
  - FUT4
  - FUT7
  - FUT9
  - GYLTL1B
  - GXYLT1
  - GXYLT2
  - LARGE
  - LFNG
  - MGAT5B
  - MFNG
  - OGT
  - POMT1
  - POMT2
  - POFUT1
  - POFUT2
  - POGLUT1
  - POMGNT1
  - RFNG
  - ST3GAL5
  - ST6GAL1
  - ST6GAL2
  - XXYLT1
  - LFNG
  - MFNG
  - RFNG
  - POMGNT2
  - POMK
- Glycosaminoglycan, chondroitin sulfate
  - B3GALT6
  - B3GAT3
  - B4GALT7
  - CHPF
  - CHPF2
  - CHST3
  - CHST7
  - CHST11
  - CHST12
  - CHST13
  - CHST14
  - CHST15
  - CHSY1
  - CHSY3
  - CSGALNACT1
  - CSGALNACT2
  - UST
  - XYLT1
  - XYLT2
- Glycosaminoglycan, heparan sulfate
  - B3GAT3
  - B3GALT6
  - B4GALT7
  - EXT1
  - EXT2
  - EXTL1
  - EXTL2
  - EXTL3
  - HS2ST1
  - HS3ST1
  - HS3ST2
  - HS3ST3A1
  - HS3ST3B1
  - HS3ST4
  - HS3ST5
  - HS6ST1
  - HS6ST2
  - HS6ST3
  - NDST1
  - NDST2
  - NDST3
  - NDST4
  - XYLT1
  - XYLT2
- Glycosaminoglycan, keratan sulfate
  - B4GAT1
  - B3GNT2
  - B3GNT7
  - B4GALT1
  - B4GALT2
  - B4GALT3
  - B4GALT4
  - CHST1
  - CHST2
  - CHST4
  - CHST5
  - CHST6
  - FUT8
  - ST3GAL1
  - ST3GAL2
  - ST3GAL3
- GPI-anchor
  - DPM2
  - GAA1
  - PIGA
  - PIGB
  - PIGC
  - PIGF
  - PIGG
  - PIGH
  - PIGK
  - PIGL
  - PIGM
  - PIGN
  - PIGO
  - PIGP
  - PIGQ
  - PIGS
  - PIGT
  - PIGU
  - PIGV
  - PIGW
  - PGIX
  - PIGY
  - PIGZ
- glycolipid, lacto/neolacto series
  - A(ABO)
  - B(ABO)
  - B3GALT1
  - B3GALT2
  - B3GALT5
  - B4GAT1
  - B3GNT2
  - B3GNT3
  - B3GNT4
  - B3GNT5
  - B4GALT1
  - B4GALT2
  - B4GALT3
  - B4GALT4
  - FUT1
  - FUT2
  - FUT3
  - FUT4
  - FUT5
  - FUT6
  - FUT7
  - FUT9
  - GCNT2
  - ST3GAL3
  - ST3GAL4
  - ST3GAL6
  - ST8SIA1
- glycolipid, ganglio series
  - B3GALT4
  - B4GALNT1
  - B4GALNT2
  - ST3GAL1
  - ST3GAL2
  - ST3GAL5
  - ST6GALNAC3
  - ST6GALNAC4
  - ST6GALNAC5
  - ST6GALNAC6
  - ST8SIA1
  - ST8SIA3
  - ST8SIA5
- glycolipid, globo series
  - A4GALT
  - B3GALT5
  - B3GALNT1
  - FUT1
  - FUT2
  - FUT9
  - GBGT1
  - ST3GAL1
  - ST3GAL2
  - ST8SIA1
- Hyaluronic acid
  - HAS1
  - HAS2
  - HAS3
- sphingolipid
  - B4GALT6
  - GAL3ST1
  - UGT8
  - UGCG
- SLC/transporter
  - SLC35A1
  - SLC35A2
  - SLC35A3
  - SLC35B1
  - SLC35B2
  - SLC35B3
  - SLC35B4
  - SLC35C1
  - SLC35D1
  - SLC35D2
- terminal modification
  - B4GALNT3
  - B4GALNT4
  - GAL3ST2
  - GAL3ST3
  - GAL3ST4
- unassign
  - FUT11
- additional
  - SFT2
  - SFT3
  - COLGALT2
  - MGAT4C
  - LHL2
  - L5
  - HS3ST6
  - COLGALT1
  - L4_nuc
  - B3GNT9
  - SFT9
  - A3GALT2
  - UGT3A1
  - GCNT7
  - ALG10B
  - ALG1L
  - ALG1L2
  - SEC1P
  - C5
  - TMEM5
  - ART1
Enzymatic Activity
- ALG
  - Doner Synthesis
    - Dol-P-Man Synthesis
      - DPM1
      - DPM2
      - DPM3
  - Dol-P-Glc Synthesis
    - ALG5
  - Cytoplasmic ALG(GnT)
    - ALG14
    - DPAGT1
    - GLT28D1
  - Cytoplasmic ALG(ManT)
    - ALG1
    - ALG11
    - ALG2
  - ER Lumen ALG(ManT)
    - ALG12
    - ALG3
    - ALG9
  - ER Lumen ALG(GlcT)
    - ALG10
    - ALG6
    - ALG8
  - Glucosyltransferases
    - UGCG
    - UGCGL1
    - UGCGL2
- Xylosyltransferases
  - XYLT1
  - XYLT2
  - GXYLT1
  - GXYLT2
  - XXYLT1
  - LARGE
  - GYLTL1B
- Fucosyltransferases
  - FUT1
  - FUT2
  - FUT3
  - FUT4
  - FUT5
  - FUT6
  - FUT7
  - FUT8
  - FUT9
  - O-Fucosyltansferases
    - POFUT1
    - POFUT2
  - Fucosyltransferases (Unknown Activities)
    - FUT10
    - FUT11
- Mannosyltransferases
  - POMT1
  - POMT2
  - PIGM
  - PIGX
  - PIGV
  - PIGB
  - PIGZ
- Galactosyltransferases
  - Ceramide
    - CGT
  - alpha
    - A4GALT
    - B(ABO)
  - beta 1,3
    - B3GALT1
    - B3GALT2
    - B3GALT4
    - B3GALT5
    - B3GALT6
    - C1GALT1
  - beta 1,4
    - B4GALT1
    - B4GALT2
    - B4GALT3
    - B4GALT4
    - B4GALT5
    - B4GALT6
    - B4GALT7
- N-Acetylgalactosaminyltransferases
  - beta 1,3
    - B3GALNT1
    - B3GALNT2
  - beta 1,4
    - B4GALNT1
    - B4GALNT2
    - B4GALNT3
    - B4GALNT4
  - UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases
    - GALNT1
    - GALNT2
    - GALNT3
    - GALNT4
    - GALNT5
    - GALNT6
    - GALNT7
    - GALNT8
    - GALNT9
    - GALNT10
    - GALNT11
    - GALNT12
    - GALNT13
    - GALNT14
    - GALNT15
    - GALNT16
    - GALNT17
    - GALNT18
    - GALNT19
    - GALNT20
  - alpha 1,3
    - A(ABO)
    - GBGT1
- N-Acetylglucosaminyltransferases
  - alpha 1,4
    - A4GNT
  - alpha 1,6
    - PIGQ
    - PIGC
    - PIGA
    - PIGH
    - PIGP
    - PIGY
    - PIGL
    - PIGW
  - beta 1,3
    - B3GNT1
    - B3GNT2
    - B3GNT3
    - B3GNT4
    - B3GNT5
    - B3GNT6
    - B3GNT7
    - B3GNT8
  - beta 1,6 (core2)
    - GCNT1
    - GCNT3
    - GCNT4
  - blood I antigen
    - GCNT2
  - MGAT family
    - MGAT1
    - MGAT2
    - MGAT3
    - MGAT4A
    - MGAT4B
    - MGAT5
    - MGAT5B
  - O-linked
    - OGT
    - EOGT
  - Protein O-linked fucose b1,3-N-acetylglucosaminyltransferases
    - MFNG
    - LFNG
    - RFNG
  - Protein O-linked mannose b1,2-N-acetylglucosaminyltransferases
    - POMGNT1
  - Protein O-linked mannose b1,4-N-acetylglucosaminyltransferases
    - POMGNT2
- Glucosyltransferase
  - B3GALTL
  - POGLUT1
  - LARGE
  - GYLTL1B
- Sialyltransferases
  - beta-Gal alpha 2,3-sialyltransferases
    - ST3GAL1
    - ST3GAL2
    - ST3GAL3
    - ST3GAL4
    - ST3GAL5
    - ST3GAL6
  - beta-Gal alpha 2,6-sialyltransferases
    - ST6GAL1
    - ST6GAL2
  - beta-GalNAc alpha 2,6-sialyltransferases
    - ST6GALNAC1
    - ST6GALNAC2
    - ST6GALNAC3
    - ST6GALNAC4
    - ST6GALNAC5
    - ST6GALNAC6
  - alpha NeuAc alpha 2,8-sialyltransferases
    - ST8SIA1
    - ST8SIA2
    - ST8SIA3
    - ST8SIA4
    - ST8SIA5
    - ST8SIA6
- GAG
  - chondroitin
    - N-Acetylgalactosaminyltransferases
      - ChGn
      - GALNACT-2
    - N-Acetylgalactosaminyltransferases Glucuronyltransferases GalNAc/GlcA
      - CHPF
      - CHSY1
      - CSS3
    - Glucuronyltransferases
      - CSGlcA-T
  - heparan sulfate
    - Glucuronyltransferases N-Acetylglucosaminyltransferases GlcA/GlcNAc
      - EXT1
      - EXT2
  - N-Acetylglucosaminyltransferases
    - EXTL1
    - EXTL3
    - EXTL2
  - Hyaluronan synthase
    - Glucuronyltransferases N-Acetylglucosaminyltransferases GAG GlcA/GlcNAc
      - HAS1
      - HAS2
      - HAS3
- Glucuronyltransferases
  - B3GAT1
  - B3GAT2
  - B3GAT3
- Sulfotransferases
  - HNK
    - CHST10
    - CHST4
    - CHST5
  - dermatan/chondroitin
    - Gal 2-O-sulfotransferase
      - UST
    - Gal 3-O-sulfotransferase
      - GAL3ST1
      - GAL3ST2
      - GAL3ST3
      - GAL3ST4
    - GalNAc 4-O-sulfotransferase
      - CHST8
      - CHST9
      - CHST12
      - CHST13
      - CHST11
    - GalNAc4S 6-O-sulfotransferase
      - GALNAC4S-6ST
  - Keratan sulfate
    - Gal 6-O-sulfotransferase
      - CHST1
      - CHST3
      - CHST7
    - GlcNAc 6-O-sulfotransferase
      - CHST6
      - CHST2
  - dermatan sulfate
    - D4ST1
  - heparan sulfate
    - 2-O-sulfotransferase
      - HS2ST1
    - 3-O-sulfotransferase
      - HS3ST1
      - HS3ST2
      - HS3ST3A1
      - HS3ST3B1
      - HS3ST4
      - HS3ST5
    - 6-O-sulfotransferase
      - HS6ST1
      - HS6ST2
      - HS6ST3
  - N-deacetylase/N-sulfotransferase
    - NDST1
    - NDST2
    - NDST3
    - NDST4
- Nucleotide Sugar Transporters
  - CMP-sialic acid transporter
    - SLC35A1
  - UDP-galactose transporter
    - SLC35A2
    - SLC35B1
  - UDP-GlcNAc transporter
    - SLC35A3
  - PAPS transporter
    - SLC35B2
  - UDP-Xyl transporter and UDP-GlcNAc transporter
    - SLC35B4
  - GDP-fucose transporter
    - SLC35C1
  - UDP-GlcA transporter and UDP-GalNAc transporter
    - SLC35D1
  - UDP-GlcNAc transporter
    - SLC35D2
  - PAPS Transporter
    - SLC35B3
- α-Dystroglycan Modification
  - FCMD
  - FKRP
- GPI EtNP Transferase
  - PIGN
  - PIGO
  - PIGF
  - PIGG
- GPI Transamidase
  - PIGK
  - GAA1
  - PIGS
  - PIGT
  - PIGU
- Others
  - POMK
  - C1GALT1C1
EC class
- 2.4.1
  - A(ABO)
  - A4GALT
  - ALG1
  - ALG12
  - ALG2
  - ALG3
  - ALG5
  - B(ABO)
  - B3GALNT1
  - B3GALT4
  - B3GALT6
  - B3GLCT
  - B3GAT1
  - B3GAT2
  - B3GAT3
  - B3GNT2
  - B3GNT3
  - B3GNT4
  - B3GNT5
  - B3GNT6
  - B4GALNT1
  - B4GALT1
  - B4GALT2
  - B4GALT3
  - B4GALT4
  - B4GALT5
  - B4GALT6
  - B4GALT7
  - C1GALT1
  - C1GALT1C1
  - CGT
  - CSGALNACT1
  - CSGALNACT2
  - CSGlcA-T
  - DPM1
  - DPM2
  - DPM3
  - EXT1
  - EXT2
  - EXTL1
  - EXTL2
  - EXTL3
  - FUT1
  - FUT2
  - FUT3
  - FUT4
  - FUT5
  - FUT6
  - FUT7
  - FUT8
  - FUT9
  - GALNT1
  - GALNT10
  - GALNT11
  - GALNT12
  - GALNT13
  - GALNT14
  - GALNT15
  - GALNT16
  - GALNT17
  - GALNT2
  - GALNT3
  - GALNT4
  - GALNT5
  - GALNT6
  - GALNT7
  - GALNT8
  - GALNT9
  - GBGT1
  - GCNT1
  - GCNT2
  - GLT28D1
  - HAS1
  - HAS2
  - HAS3
  - LFNG
  - MFNG
  - MGAT1
  - MGAT2
  - MGAT3
  - MGAT4A
  - MGAT4B
  - MGAT5
  - MGAT5B
  - PIGA
  - PIGB
  - PIGC
  - PIGH
  - PIGM
  - PIGP
  - PIGQ
  - PIGV
  - PIGX
  - PIGY
  - PIGZ
  - POMT1
  - POMT2
  - RFNG
  - UGCG
- 2.4.2
  - XYLT1
  - XYLT2
- 2.4.99
  - ST3GAL1
  - ST3GAL2
  - ST3GAL3
  - ST3GAL4
  - ST3GAL5
  - ST3GAL6
  - ST6GAL1
  - ST6GAL2
  - ST6GALNAC1
  - ST6GALNAC2
  - ST6GALNAC4
  - ST8SIA1
- 2.7.8
  - DPAGT1
- 2.8.2
  - CHST1
  - CHST11
  - CHST12
  - CHST13
  - CHST2
  - CHST3
  - CHST4
  - CHST5
  - CHST6
  - CHST7
  - CHST8
  - CHST9
  - GAL3ST1
  - GAL3ST2
  - GAL3ST3
  - GAL3ST4
  - HS2ST1
  - HS3ST1
  - HS3ST2
  - HS3ST3A1
  - HS3ST3B1
  - HS3ST4
  - HS3ST5
  - NDST1
  - NDST2
  - NDST3
  - NDST4
- 3.5.1
  - PIGL

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GlycoGene DataBase

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GG Family

GG Family

Galactosyltransferase

Orthologous Gene

Drosophila melanogaster

Rattus norvegicus

Mus musculus

Acceptor Substrates (Reference)

A family of human beta4-galactosyltransferases. Cloning and expression of two novel UDP-galactose:beta-n-acetylglucosamine beta1, 4-galactosyltransferases, beta4Gal-T2 and beta4Gal-T3.

DONOR : UDP-Gal

Transferred

Not Transferred

Molecular cloning of a human cDNA encoding beta-1,4-galactosyltransferase with 37% identity to mammalian UDP-Gal:GlcNAc beta-1,4-galactosyltransferase.

DONOR : UDP-Gal

Transferred

Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions.

Beta 1,4-galactosyltransferase (beta 4GalT)-IV is specific for GlcNAc 6-O-sulfate. Beta 4GalT-IV acts on keratan sulfate-related glycans and a precursor glycan of 6-sulfosialyl-Lewis X.

Strategy for the fine characterization of glycosyltransferase specificity using isotopomer assembly.

Acceptor Substrates (KEM-C)

Expression

A family of human beta4-galactosyltransferases. Cloning and expression of two novel UDP-galactose:beta-n-acetylglucosamine beta1, 4-galactosyltransferases, beta4Gal-T2 and beta4Gal-T3.

Molecular cloning of a human cDNA encoding beta-1,4-galactosyltransferase with 37% identity to mammalian UDP-Gal:GlcNAc beta-1,4-galactosyltransferase.

The expanding beta 4-galactosyltransferase gene family: messages from the databanks.

Beta 1,4-galactosyltransferase (beta 4GalT)-IV is specific for GlcNAc 6-O-sulfate. Beta 4GalT-IV acts on keratan sulfate-related glycans and a precursor glycan of 6-sulfosialyl-Lewis X.

Biological Resources