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B4GALT6
JCGG-STR031569 JCGG-STR001961
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6 (B4GALT6) transfers galactose to glucosylceramide. B4GALT6 is also known as β4GalT-IV and β-1,4-galactosyltransferase 6. B4GALT family is consist of 7 β-1,4-galactosyltransferases, which show different substrate specificity and expression patterns. B4GALT6 is considered as a lactosylceramide (LacCer) synthase important for glycolipid biosynthesis. (However, LacCer synthase activity was decreased in B4GALT5-deficient mice, but the activity was not confirmed in vitro.)

Galactosyltransferase

GGDB SymbolB4GALT6
Alias beta3GalT6    details
Designationbeta 1,4-galactosyltransferase 6
OrganismHomo sapiens
GeneID 9331
HGNC 929
mRNA NM_004775       (CDS)
Protein NP_004766       (CDS)
map18q11
EC# 2.4.1.22   
CAZy GT7   
OMIM 604017   

Orthologous Gene

Acceptor Substrates (Reference)

Acceptor Substrates (KEM-C)

Expression

Biological Resources
This page does not indicate all of the enzymatic reaction, and expression of "B4GALT6".