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HO-Ser/Thr GalNAc(alpha1-O)-Ser/Thr
This enzyme catalyzes the GalNAc-transfer from UDP-GalNAc to Ser or Thr residue in the protein. The product is GalNAc-alpha-O-Ser/Thr structure, so-called Tn-antigen, which is the base structure of mucin type O-glycan. The acceptor substrate (protein) is typically Mucin. GALNT3 is the third member of this enzyme family. In general, this isozyme exhibits strong activities toward continuous S/T sequence, producing the triplet Tn-structure.
O-glycan Tn-antigen mucin tumor marker

UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase

Alias MGC61909, GalNAc-T3    details
DesignationUDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3
OrganismHomo sapiens
GeneID 2591
HGNC 4125
mRNA NM_004482       (CDS)
Protein NP_004473       (CDS)
CAZy GT27   
OMIM 601756   
This page does not indicate all of the enzymatic reaction, and expression of "GALNT3".