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HO-Ser/Thr GalNAc(alpha1-O)-Ser/Thr
This enzyme catalyzes the GalNAc-transfer from UDP-GalNAc to Ser or Thr residue in the protein. The product is GalNAc-alpha-O-Ser/Thr structure, so-called Tn-antigen, which is the base structure of mucin type O-glycan. The acceptor substrate (protein) is typically Mucin. GALNT6 is the sixth member of this enzyme family. This was discovered as a highly homologous gene with GALNT3, but its function is not redundant with T3.

O-glycan Tn-antigen mucin tumor marker

UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase

Alias GALNAC-T6, GalNAcT6    details
DesignationUDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6
OrganismHomo sapiens
GeneID 11226
HGNC 4128
mRNA BC035822       (CDS)
Protein AAH35822       (CDS)
CAZy GT27   
OMIM 605148   
This page does not indicate all of the enzymatic reaction, and expression of "GALNT6".