GlycoGene DataBase

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The product from this gene is highly homologous to GalNAc-transferase family. Actual enzymatic activity of GalNAc-transfer is, however, not significant, since Trp residue in the functional motif, WGGEN(Q), is replaced with Tyr. Other putative isozymes with similar amino-acid-substitution are found as GALNT9, T18 and T19.

O-glycan Tn-antigen mucin tumor marker

UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase

Alias GALNAC-T8    details
DesignationUDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 8
OrganismHomo sapiens
GeneID 26290
HGNC 4130
mRNA NM_017417       (CDS)
Protein NP_059113       (CDS)
CAZy GT27   
OMIM 606250   
This page does not indicate all of the enzymatic reaction, and expression of "GALNT8".