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HO-Ser/Thr GalNAc(alpha1-O)-Ser/Thr
This enzyme catalyzes the GalNAc-transfer from UDP-GalNAc to Ser or Thr residue in the protein. The product is GalNAc-alpha-O-Ser/Thr structure, so-called Tn-antigen, which is the base structure of mucin type O-glycan. The acceptor substrate (protein) is typically Mucin. GALNT13 is the 13th member of this enzyme family. This isozyme is highly homologous to GALNT1, however this is specifically expressed in neurons, suggesting the synthesis of neuron specific Tn-antigens.
O-glycan Tn-antigen mucin tumor marker

UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase

Alias FLJ16031, FLJ41157, KIAA1918, MGC119459, MGC119461, GalNAc-T13    details
DesignationUDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13
OrganismHomo sapiens
GeneID 114805
HGNC 23242
mRNA NM_052917       (CDS)
Protein NP_443149       (CDS)
CAZy GT27   
OMIM 608369   
This page does not indicate all of the enzymatic reaction, and expression of "GALNT13".