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HO-Ser/Thr GalNAc(alpha1-O)-Ser/Thr
This enzyme catalyzes the GalNAc-transfer from UDP-GalNAc to Ser or Thr residue in the protein. The product is GalNAc-alpha-O-Ser/Thr structure, so-called Tn-antigen, which is the base structure of mucin type O-glycan. The acceptor substrate (protein) is typically Mucin. GALNT15 is the 15th member of this enzyme family. This isozyme exhibits unique catalytic activity producing multiple-GalNAc peptides.

O-glycan Tn-antigen mucin tumor marker

UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase

Alias GALNT16, GALNT20, GALNTL3, DKFZp434I2216, DKFZp761D2324, PIH5, GALNT7, GALNT13, GALNTL2    details
DesignationUDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase T15
OrganismHomo sapiens
GeneID 117248
HGNC 21531
mRNA AB078149       (CDS)
Protein BAD29961       (CDS)
CAZy GT27   
OMIM 615131   
This page does not indicate all of the enzymatic reaction, and expression of "GALNT15".