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JCGG-STR008276 JCGG-STR029533
β1,4-N-acetylgalactosaminyltransferase-III (B4GALNT3) transfers GalNAc from UDP-GalNAc to GlcNAcβ-R, synthesizing N,N'-diacetyllactosamine, GalNAcβ1→4GlcNAc (LacdiNAc) on N- and O-glycans. B4GALNT3 is also known as B4GalNac-T3. LacdiNAc structures are also synthesized by its homologue B4GALNT4, and occur on various glycoproteins including lutropin (LH), thyrotropin (TSH), zona pellucida 3 (ZP3), and extracellular matrix glycoproteins. LDN can be further modified with sulfation, sialylation, and fucosylation, indicating important roles of LacdiNAc structures in vivo.


Alias FLJ16224, FLJ40362, B4GalNac-T3    details
Designationbeta 1,4 N-acetylgalactosaminyltransferase 3
OrganismHomo sapiens
GeneID 283358
HGNC 24137
mRNA NM_173593       (CDS)
Protein NP_775864       (CDS)
OMIM 612220   
This page does not indicate all of the enzymatic reaction, and expression of "B4GALNT3".